PPA constraints need to be paired with real workloads, but they also need to be flexible to account for future changes.

In silico antibody accessibility analysis indicates that ectodomain epitopes are transiently exposed, while MPER epitopes are virtually always occluded in the pre-fusion trimer.

This important study, which tackles the challenge of analyzing genome integrity and instability in unicellular pathogens by introducing a novel single-cell genomics approach, presents compelling ...

Background Patients with severe aortic stenosis (AS) are at high risk of mortality, regardless of symptom status. Despite ...